Progressive liver calcifications in neonatal coxsackievirus infection

Coxsackievirus group B can cause a severe systemic disease in the perinatal period. Severe manifestations like meningitis, encephalitis, hepatitis, an d myocarditis have been previously reported. A case of a twin neonate infec ted by coxsackievirus group B is described, who developed progressive exten sive hepatic calcifications demonstrated by ultrasound and computed tomogra phy with follow-up. Hepatic calcifications in coxsackievirus infection have not been previously reported.