Brucellosis: unusual presentations in two adolescent boys

Two boys presented with variable signs and symptoms of infectious disease t hat challenged diagnosis. One of the two patients had aortic valve vegetati ons and lower extremity aneurysms, and the other had calvarial osteomyeliti s, epidural abscess, pleural effusions, and pulmonary nodules. Only after a battery of bacterial and fungal agglutination tests was the unsuspected di agnosis made in each of brucellosis from Brucella canis.