Chalconoids from Fissistigma bracteolatum

Phytochemical studies on the leaves of Fissistigma bracteolatum yielded bes ides the two known compounds 2-hydroxy-3,4,6-trimethoxychalcone (1) and 5,7 ,8-trimethoxyflav-3-ene (2), five new chalconoids 2-hydroxy-3,4,6-trimethox ychalcene (3), 2-hydroxy-3,4,6-trimethoxydihydrochalcone (4), 2'-hydroxy-3' ,4',6'-trimethoxydihydrochalcone (5), 2'-hydroxy-3',4',6'-trimethoxy-beta'- methoxychalcane (6) and 2'-hydroxy-3',4',6'-trimethoxy-beta'-ethoxychalcane (7). The structures of these compounds were determined by mass and NMR spe ctroscopic methods. (C) 2000 Elsevier Science Ltd. All rights reserved.