Our objectives were to: (1) develop a self-report questionnaire for measuri
ng the impact of migraine headache on work; and (2) qualitatively assess as
pects of its performance. Two samples of migraine sufferers provided the da
ta. Sample 1 (n = 18) participated in a structured discussion group designe
d to elicit examples of migraine's on-the-job impact. Sample 2 (n = 11) com
pleted a mail survey and participated in in-depth phone interviews. Intervi
ews addressed item comprehensibility, consistency of interpretation, the co
gnitive processes by which certain answers were generated and response burd
en. The participants were currently employed men and women, at least 18 yea
rs of age, who met the International Headache Society (IHS) criteria for mi
graine headache [1]. Discussion group participants indicated that migraine
attacks substantially diminished their job performance. Pain, photophobia,
phonophobia, mental impairment and fatigue were perceived as interfering wi
th even routine or relatively simple job tasks. The Migraine Work and Produ
ctivity Loss Questionnaire, Version 1.0(C) (MWPLQ(C))* was written. Next, i
t was assessed in the context of the in-depth interviews. Result indicated
that the MWPLQ was comprehended without difficulty, interpreted consistentl
y and easy to complete. Thus, qualitative results provide initial support f
or the new questionnaire.