Synthesis of N-alkyl-(alpha-aminoalkyl)phosphine oxides and phosphonic esters as potential HIV-protease inhibitors, starting from alpha-aminoacids

Authors
Alonso, E Alonso, E Solis, A del Pozo, C
Citation
E. Alonso et al., Synthesis of N-alkyl-(alpha-aminoalkyl)phosphine oxides and phosphonic esters as potential HIV-protease inhibitors, starting from alpha-aminoacids, SYNLETT, (5), 2000, pp. 698-700
Citations number
14
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
5
Year of publication
2000
Pages
698 - 700
Database
ISI
SICI code
0936-5214(200005):5<698:SONOAP>2.0.ZU;2-K
Abstract
The synthesis of alpha-aminophosphonic acid derivatives starting from alpha -aminoacids is described. These phosphorus peptide mimics could be potentia l HIV-protease inhibitors.