Cobalt(II) chloride-catalyzed chemoselective sodium borohydride reduction of azides in water

Authors
Fringuelli, F Pizzo, F Vaccaro, L
Citation
F. Fringuelli et al., Cobalt(II) chloride-catalyzed chemoselective sodium borohydride reduction of azides in water, SYNTHESIS-S, (5), 2000, pp. 646-650
Citations number
37
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
5
Year of publication
2000
Pages
646 - 650
Database
ISI
SICI code
0039-7881(200005):5<646:CCCSBR>2.0.ZU;2-W
Abstract
Reduction of azides to amines and amides was carried out with NaBH4/CoCl2. 6H(2)O in sole water at 25 degrees C under catalytic heterogeneous conditio ns. A broad spectrum of azides was reduced in a short time, chemoselectivel y in high yield and purity.