A convergent route to 5-(arylsulfanyl)-6-sulfonamido-3-benzofuranones

Authors
Bosch, J Roca, T Catena, JL Farrerons, C Miquel, I
Citation
J. Bosch et al., A convergent route to 5-(arylsulfanyl)-6-sulfonamido-3-benzofuranones, SYNTHESIS-S, (5), 2000, pp. 721-725
Citations number
11
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
5
Year of publication
2000
Pages
721 - 725
Database
ISI
SICI code
0039-7881(200005):5<721:ACRT5>2.0.ZU;2-4
Abstract
A procedure for the synthesis of 5-(arylsulfanyl)-2,3-dihydro-6-sulfonamido -3-benzofuranones (1) via 5-bromo-3-methoxy-6-nitrobenzofuran (4) as a comm on advanced synthetic intermediate has been developed. The key step consist s of a regioselective nucleophilic aromatic substitution of the bromine ato m of 4 by an aryl or heteroarylthiol.