Indole alkaloids by a chemoenzymatic approach: two convergent routes for the first enantioselective synthesis of (+)-20R-15,20-dihydrocleavamine

Authors
Danieli, B Lesma, G Passarella, D Silvani, A
Citation
B. Danieli et al., Indole alkaloids by a chemoenzymatic approach: two convergent routes for the first enantioselective synthesis of (+)-20R-15,20-dihydrocleavamine, TETRAHEDR L, 41(18), 2000, pp. 3489-3492
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
18
Year of publication
2000
Pages
3489 - 3492
Database
ISI
SICI code
0040-4039(20000429)41:18<3489:IABACA>2.0.ZU;2-U
Abstract
A stereocontrolled total synthesis of the title compound is described, star ting from enantiopure intermediates. Two alternative strategies have been d eveloped to ensure the critical formation of the nine-membered ring of 3. ( C) 2000 Elsevier Science Ltd. All rights reserved.