Camphordisulfonamides: good chiral ligands for the addition of dialkylzincto aliphatic aldehydes

Citation
O. Prieto et al., Camphordisulfonamides: good chiral ligands for the addition of dialkylzincto aliphatic aldehydes, TETRAHEDR-A, 11(7), 2000, pp. 1629-1644
Citations number
58
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
11
Issue
7
Year of publication
2000
Pages
1629 - 1644
Database
ISI
SICI code
0957-4166(20000420)11:7<1629:CGCLFT>2.0.ZU;2-W
Abstract
The preparation of several disulfonamides derived from camphor and their us e in the titanium tetra-isopropoxide-promoted enantioselective addition of dialkylzinc to aldehydes is described. The enantiomeric ratio is up to 98:2 , the best results being obtained for aliphatic aldehydes. (C) 2000 Elsevie r Science Ltd. All rights reserved.