V. Kaden et al., Oral immunisation of wild boar against classical swine fever: evaluation of the first field study in Germany, VET MICROB, 73(2-3), 2000, pp. 239-252
The effectiveness of oral immunisation of wild boar against classical swine
fever (CSF) was studied in a field trial in Lower Saxony for two years, fr
om 1993 to 1995. This field study was performed in an area of ca. 270 km(2)
, belonging to three military training grounds. Wild boar in one range were
uninfected, whilst the wild boar population of the other two ranges were i
nfected with CSF virus. The animals were vaccinated with a bait vaccine. Th
e immunisation procedure included a double vaccination with an interval of
approximate to 14 days. This was followed by repeated vaccination campaigns
at 6 monthly intervals. The rate of uptake of baits at feeding places was
determined to be between 85 and 100%. The bait marker oxytetracycline could
be detected in bone samples in 52.4-67.6% of hunted animals. The antibody
prevalence reached 49-60.3% after immunisation. However, >50% of young boar
s did not feed on vaccine baits nor become immunised. Therefore, an intensi
ve hunting of this age group is a necessary adjunct to the use of oral vacc
ination. After the third immunisation period, no virus was detected in the
areas where oral immunisation took place. (C) 2000 Elsevier Science B.V. Al
l rights reserved.