B. Lu et al., INEFFECTIVE DIASTOLIC FILLING IN TACHYCARDIA-INDUCED CARDIOMYOPATHY WITH TOTAL PULSUS ALTERNANS, Journal of the American Society of Echocardiography, 10(1), 1997, pp. 88-92
We report a case of total pulse alternans in a patient with paroxysmal
ectopic atrial tachycardia and echocardiographic findings obtained be
fore and after radiofrequency catheter ablation (RFCA) that terminated
the arrhythmia. The patient was a 27-year-old man with history of par
oxysmal palpitations with worsening episodic dizziness, chest tightnes
s, and dyspnea. Electrocardiography (EGG) showed atrial tachycardia at
160 to 170 beats/min while the simultaneous pulse was in the 80s beat
s/min. Echocardiogram showed that aortic and mitral valves opened with
alternating excursions and outflow velocities. Furthermore, despite s
imilar ventricular wall thickening during systole of consecutive cardi
ac cycles, there was alternating mitral valve opening during diastole
of tile same cycles, providing direct evidence that ineffective diasto
lic filling and mitral valve opening may play a role in the pathogenes
is of pulse alternans. Repeat ECG and echocardiography after the succe
ssful RFCA showed normal sinus rhythm and normal opening excursion and
the velocity across the aortic and mitral valves.