In current theories of sinusitis obstruction at the ostiomeatal comple
x leads to localized inflammation and infection. Haller cells, an exte
nsion of ethmoid ethmoid pneumatization along the maxillary antrum roo
f; have also been suggested as a causative factor in sinusitis because
of their ability to cause narrowing of the infundibulum. Coronal CT s
cans were reviewed in 154 patients to evaluate the role of Haller cell
s in sinusitis. Haller cells were present in 34% of patients. The cell
s were graded as small, medium, or large, and correlated with radiolog
ic evidence of sinusitis (e.g., mucosal thickening or opacification).
A statistically significant increase in maxillary sinus mucosal diseas
e was noted in patients with medium or large Haller cells (45.8%) vers
us those with small cells (28.9%, p < 0.05). Thus obstructive medium a
nd large Haller cells may be an etiologic factor in sinusitis.