"Bite-and-switch" approach to creatine recognition by use of molecularly imprinted polymers

Authors
Subrahmanyam, S Piletsky, SA Piletska, EV Chen, BN Day, R Turner, APF
Citation
S. Subrahmanyam et al., "Bite-and-switch" approach to creatine recognition by use of molecularly imprinted polymers, ADVAN MATER, 12(10), 2000, pp. 722
Citations number
12
Categorie Soggetti
Multidisciplinary,"Material Science & Engineering
Journal title
ADVANCED MATERIALS
ISSN journal
09359648 → ACNP
Volume
12
Issue
10
Year of publication
2000
Database
ISI
SICI code
0935-9648(20000517)12:10<722:"ATCRB>2.0.ZU;2-8
Abstract
The detection of creatine is important in the analysis of athletes and body builders. Here is reported the preparation of a synthetic polymer using im printing polymerization, which leaves the polymer with receptor-mimicking r ecognition sites that are specific for creatine. Molecular recognition resu lts in a fluorescent complex (see Figure) and thus represents a ''bite-and- switch" mechanism.