S. Subrahmanyam et al., "Bite-and-switch" approach to creatine recognition by use of molecularly imprinted polymers, ADVAN MATER, 12(10), 2000, pp. 722
The detection of creatine is important in the analysis of athletes and body
builders. Here is reported the preparation of a synthetic polymer using im
printing polymerization, which leaves the polymer with receptor-mimicking r
ecognition sites that are specific for creatine. Molecular recognition resu
lts in a fluorescent complex (see Figure) and thus represents a ''bite-and-
switch" mechanism.