Despite advances in the availability and quality of antihypertensive medica
tions and the institution of national programs to educate people about the
seriousness of hypertension, much remains to be done. The percentages of pe
ople who are aware of their disease, are being treated for it, and are achi
eving adequate control of their blood pressure (BP) are disconcertingly low
worldwide; surveys in numerous countries have consistently shown that fewe
r than 60% of affected people are being treated for hypertension and fewer
than 30% have their BP adequately controlled. Reluctance on the part of man
y physicians to use antihypertensive therapy aggressively may be an impedim
ent to improving these numbers. Further clinical trials are needed to asses
s the extent to which BP could be lowered safely and effectively with both
single-agent and combination therapies. Am J Hypertens 2000;13:57S-61S (C)
2000 American Journal of Hypertension, Ltd.