Identification of monozygotic twins that are concordant for preeclampsia

Authors
O'Shaughnessy, KM Ferraro, F Fu, BY Downing, S Morris, NH
Citation
Km. O'Shaughnessy et al., Identification of monozygotic twins that are concordant for preeclampsia, AM J OBST G, 182(5), 2000, pp. 1156-1157
Citations number
3
Categorie Soggetti
Reproductive Medicine","da verificare
Journal title
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
ISSN journal
00029378 → ACNP
Volume
182
Issue
5
Year of publication
2000
Pages
1156 - 1157
Database
ISI
SICI code
0002-9378(200005)182:5<1156:IOMTTA>2.0.ZU;2-Y
Abstract
Preeclampsia is thought to be discordant in monozygotic twins. While recrui ting for a genetic study into preeclampsia, we identified 4 sets of twins a nd a triplet gestation; all were monozygous on deoxyribonucleic acid "finge rprinting." Two twins were concordant for preeclampsia, and 2 of the triple ts had pregnancy-induced hypertension, although only 1 of them had proteinu ria. Hence we confirm the existence of monozygotic twins that are concordan t for preeclampsia.