MR imaging differentiation of soft-tissue hemangiomas from malignant soft-tissue masses

OBJECTIVE. The purpose of this study was to determine whether MR imaging fe atures can reliably distinguish hemangiomas from malignant soft-tissue mass es. MATERIALS AND METHODS. We retrospectively reviewed MR imaging studies of 22 patients with soft-tissue hemangiomas and 22 patients with malignant soft- tissue masses. Images were reviewed and agreement reached by a consensus in terpretation of two observers and by an independent observer. Masses were e valuated for signal intensity on T1- and T2-weighted images, for enhancemen t with gadolinium administration, and for morphology (lobulation, septation , central low-intensity dots), Lesion T2 signal and lesion enhancement with gadolinium administration were also objectively measured using regions of interest and comparison with skeletal muscle. RESULTS, Signal intensity on T1-weighted imaging of hemangiomas and maligna nt soft-tissue masses was similar. Subjective analysis showed greater T2 si gnal and gadolinium enhancement in hemangiomas; however, the differences we re not statistically significant on objective analysis, Lobulation, septati on, and central low-signal-intensity dots were all mon common in hemangioma s, with statistical significance achieved; the combination of all three fin dings was specific for hemangioma. CONCLUSION. Although no single MR imaging feature was diagnostic in this st udy, analysis of lesion morphology, signal intensity, and enhancement with gadolinium allowed MR imaging differentiation of hemangiomas from malignant soft-tissue masses.