Maintenance treatments for opiate dependence in specialized care centers: the OPPIDUM program of the Centers of Evaluation and Information on Pharmacodependence.
X. Thirion et al., Maintenance treatments for opiate dependence in specialized care centers: the OPPIDUM program of the Centers of Evaluation and Information on Pharmacodependence., ANN MED IN, 151, 2000, pp. A10-A17
The aim of this study was to analyze information concerning multiple drug a
ddiction, illicit behaviors and use of the venous route by maintenance trea
tment patients included in the October 1998 survey of the OPPIDUM program.
Among 1.462 observations, 71% of the subjects were taking maintenance treat
ments (60% high-dose buprenorphine and 40% methadone). High-dose buprenorph
ine was taken without medical supervision in 10% of cases, Indicators of ab
use were high in this case: multiple drug addiction and intravenous use of
buprenorphine (28%). Patients maintained by methadone were older and living
in better socio-economic conditions than patients maintained by high-dose
buprenorphine. However, in the two groups, the percentage of patients using
the intravenous route was the same (15% and 21%). More cocaine was used by
the methadone group (16% versus 7%).
Thirty-seven percent of the subjects maintained on high-dose buprenorphine
were followed by a general practitioner. They appeared to be more unbalance
d and in more precarious condition than subjects treated in specialized car
e centers but they were not representative of the patients maintained by bu
prenorphine, It would be important to determine why these subjects consult
a specialized care center.