Three-dimensional simulations of hydrodynamic jets are computed at rather h
igh resolution using the ZEUS-3D code. The parameters we employ are suitabl
e for moderate-to-high-power radio jets emerging through a galactic atmosph
ere or halo and eventually crossing a tilted pressure-matched interface wit
h a hotter intracluster medium. Before they cross this interface, these sim
ulations aim the jets so that they hit massive clouds within the galactic h
alo, with densities 10 or more times higher than the ambient atmospheric de
nsity and hundreds to thousands times the jet density. Such clouds are set
up with radii several times that of the jet and could correspond to giant m
olecular cloud complexes or small cannibalized galaxies. We find that while
powerful jets eventually disperse the clouds, for off-center collisions, n
onaxisymmetric instabilities are induced in those jets. Those instabilities
grow faster for lower Mach number jets and can disrupt the jets substantia
lly sooner than occurs for similar simulations of jets not hitting clouds.
Such interactions could be related to some compact steep-spectrum source mo
rphologies. Weak jets can be effectively halted or destroyed by reasonably
massive clouds, and this type of interaction may have relevance for the pau
city of extended radio jets in spiral galaxies. Slow, dense jets may be ben
t yet remain stable for fairly extended times, and such interactions can be
responsible for some of the wide-angle tail and most of the "dogleg" radio
source morphologies.