Citation
Ga. Kraus et Xm. Wang, Synthesis and endothelin receptor binding activity of synthetic analogues of RES-1149-2, BIOORG MED, 10(9), 2000, pp. 895-897
Citations number
18
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X
→ ACNP
Volume
10
Issue
9
Year of publication
2000
Pages
895 - 897
Database
ISI
SICI code
0960-894X(20000501)10:9<895:SAERBA>2.0.ZU;2-L
Abstract
A direct synthesis of analogues 6 and 7 is described. The key transformatio
ns are the addition of dibromomethyl lithium to a ketone and the subsequent
mild hydrolysis to a hemiacetal. (C) 2000 Elsevier Science Ltd. All rights
reserved.