Anomalous temperature dependence of peptide films at air-water interface

Authors
Jayakumar, R Murugesan, M
Citation
R. Jayakumar et M. Murugesan, Anomalous temperature dependence of peptide films at air-water interface, BIOORG MED, 10(10), 2000, pp. 1055-1057
Citations number
33
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
10
Issue
10
Year of publication
2000
Pages
1055 - 1057
Database
ISI
SICI code
0960-894X(20000515)10:10<1055:ATDOPF>2.0.ZU;2-A
Abstract
The tetrapeptide derivative Tyr-Gly-Phe-Ala-OBz (1) forms monolayers as con firmed by compressibility studies carried out at various temperatures. Pept ide 1 monolayer exhibits an anomalous structural transition at 40 degrees C as evidenced by pi-A isotherms recorded at different temperatures. The str uctural transition is also observed in aqueous solution of trifluoroacetate of peptide 1 as evidenced by fluorescence and Raman scattering intensity m easurements. (C) 2000 Elsevier Science Ltd. All rights reserved.