Alcohol consumption and cigarette smoking in relation to high frequency ofp53 protein accumulation in oesophageal squamous cell carcinoma in the Japanese

Authors
Saeki, H Ohno, S Araki, K Egashira, A Kawaguchi, H Ikeda, Y Morita, M Kitamura, K Sugimachi, K
Citation
H. Saeki et al., Alcohol consumption and cigarette smoking in relation to high frequency ofp53 protein accumulation in oesophageal squamous cell carcinoma in the Japanese, BR J CANC, 82(11), 2000, pp. 1892-1894
Citations number
13
Categorie Soggetti
Oncology,"Onconogenesis & Cancer Research
Journal title
BRITISH JOURNAL OF CANCER
ISSN journal
00070920 → ACNP
Volume
82
Issue
11
Year of publication
2000
Pages
1892 - 1894
Database
ISI
SICI code
0007-0920(200006)82:11<1892:ACACSI>2.0.ZU;2-M
Abstract
We investigated levels of p53 protein expression in Japanese patients with oesophageal squamous cell carcinoma. A significantly larger proportion of h eavy alcohol drinkers and cigarette smokers was evident in the p53-positive group. The combination of drinking and smoking was associated with a high frequency of p53 protein accumulation. (C) 2000 Cancer Research Campaign.