A 43-year-old male patient was diagnosed as having hepatocellular carcinoma
with portal vein thrombosis and arterioportal shunts. Three-dimensional co
nformal radiation therapy (3DCRT) with high focal dose was given to the lef
t portal venous area. Shrinkage of the tumour and thrombus, disappearance o
f the arterioportal shunts and restoration of the hepatopedal now of the po
rtal vein was noted 3 months after treatment. The patient received further
transarterial embolisation and achieved successful tumour control. No serio
us complications were encountered. 3DCRT is technically feasible and effect
ive to treat a small volume of liver tissue with a high dose of radiation i
n this advanced disease.