An uncommon tumor of the urinary bladder: the small cell carcinoma

Primary small cell carcinoma of the urinary bladder in an uncommon tumor, c ompared to the frequency of urothelial tumors. Fifty percent of cases are c ombined with a non endocrine carcinomas component. we report six new cases of this tumor, three of pure, and three associated with an urothelial carci noma. Diagnosis is easy established by the immunohistochemical study which show the neuro-endocrine differentiation of these agressive tumors. Patholo gist needs to look for a neuro-endocrine part in all bladder cancer, as its presence modify the treatment. Chimiotherapy is used in these cancers, due to high metastatic power. Places of radical surgery and radiotherapy need to be specified.