Palladium/phosphite catalyst systems for efficient cross coupling of aryl bromides and chlorides with phenylboronic acid

Authors
Zapf, A Beller, M
Citation
A. Zapf et M. Beller, Palladium/phosphite catalyst systems for efficient cross coupling of aryl bromides and chlorides with phenylboronic acid, CHEM-EUR J, 6(10), 2000, pp. 1830-1833
Citations number
36
Categorie Soggetti
Chemistry
Journal title
CHEMISTRY-A EUROPEAN JOURNAL
ISSN journal
09476539 → ACNP
Volume
6
Issue
10
Year of publication
2000
Pages
1830 - 1833
Database
ISI
SICI code
0947-6539(20000515)6:10<1830:PCSFEC>2.0.ZU;2-F
Abstract
The Suzuki reaction of aryl bromides is efficiently catalyzed by palladium/ phosphite complexes generated in situ. The influence of ligand, base, and d ifferent additives is examined. The process tolerates various functional gr oups and catalyst turnover numbers up to 820 000 are obtained even with dea ctivated aryl bromides. For the first time it is shown that palladium/phosp hite complexes also catalyze efficiently the Suzuki reaction of aryl chlori des.