Solitary cutaneous metastasis on the buttock: a disclosing sign of pancreatic adenocarcinoma

A 48-year-old man, previously healthy and asymptomatic, showed a unique ski n lesion located on the right buttock. The histopathological study of the l esion disclosed an adenocarcinoma metastatic to the skin. The primary tumou r was found at the head of the pancreas, and was confirmed by biopsy. Six m onths after the beginning of treatment with Gemcitabine the patient is stil l asymptomatic, and the cutaneous lesion has disappeared. Carcinomas of the pancreas represent less than 5% of human malignant neoplasms, skin involve ment is rare, and metastasis generally multiple and situated in the periumb ilical area. To our knowledge, very few patients have been reported with a solitary cutaneous lesion disclosing a pancreatic adenocarcinoma. The atypi cal location, the absence of related symptoms or analytical disorders, and the good progress of the patient make this case especially interesting.