V. Papantoniou et al., Scintimammographic findings of in situ ductal breast carcinoma in a double-phase study with Tc-99m(V) DMSA and Tc-99m MIBI value of Tc-99m(V) DMSA, CLIN NUCL M, 25(6), 2000, pp. 434-439
The authors present a case of in situ ductal carcinoma of the breast (DCIS)
with no associated mass in a 46-year-old woman examined with Tc-99m MIBI a
nd Tc-99m(V) DMSA scans, which were acquired in separate sessions 10 minute
s and 60 minutes after injection. Histologic analysis revealed a small (<1
cm) infiltrating ductal carcinoma located within the DCIS. Mammography show
ed a cluster of microcalcifications on a very dense parenchymal background.
Tc-99m(V) DMSA was characterized as positive for DCIS, especially in the d
elayed image. Tc-99m MIBI failed to identify the lesions previously noted.
In conclusion, Tc-99m(V) DMSA scintimammography seems to have an advantage
and could improve the detection of nonpalpable in situ breast carcinomas.