Accurate assessment of diabetic patients requires cooperation between owner
s and veterinarians as well as evaluation of all data, including resolution
of clinical signs, serial blood glucose levels, and possibly serum glycosy
lated protein concentrations. in evaluating serial blood glucose curves, bo
th the duration of action and nadir of glucose concentration must be assess
ed and changes in insulin dose or frequency made accordingly. Glycosylated
protein concentrations may help determine the adequacy of ongoing control.
Development of hypoglycemia or hyperglycemia in a previously well-controlle
d patient suggests a change in either endogenous or exogenous factors, and
a cause should be determined. Hypoglycemia should he avoided and treated ag
gressively if it does occur. If insulin resistance is present, the cause sh
ould be delineated and removed if possible.