Body composition in nutritionally adequate ambulatory and non-ambulatory children with cerebral palsy and a healthy reference group

Bone-mineral content (BMC; g) and density (BMD; g/cm(2)) were measured by d ual energy X-ray absorptiometry in the proximal femur, femoral neck, and to tal body of nutritionally adequate children (n=17; 11 girls, six boys; aged 7.6 to 13.8 years) with spastic cerebral palsy (GP), Bone-mineral-free lea n tissue (BMFL; g) and fat mass (FM; g) were obtained from total body scans . Chronological and developmental age-based z scores for the children with CP were derived from a pediatric database (n=894). Children with CP had BMC z scores from -1.8 (total body) to -3.2 (femoral neck) SDs below the norma tive sample. Non-independent ambulators had lower z scores for total body B MD, femoral neck BMD, and BMC than independent ambulators, The BMFL z score of individuals with GP was 2 SDs below that of the reference group and hig her in the independent ambulators than in the non-independent ambulators, w hereas FM deviated little. These findings suggest that non-nutritional fact ors, such as ambulation, account for the low BMC, BMD, and BMFL tissue obse rved in this population.