Characterization of the physicochemical properties of the micelles of platelet-activating factor (C-18 : 0)

Authors
Asai, Y Nomura, T Murahashi, N Iwamoto, K
Citation
Y. Asai et al., Characterization of the physicochemical properties of the micelles of platelet-activating factor (C-18 : 0), DRUG DEV IN, 26(6), 2000, pp. 671-674
Citations number
23
Categorie Soggetti
Pharmacology & Toxicology
Journal title
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
ISSN journal
03639045 → ACNP
Volume
26
Issue
6
Year of publication
2000
Pages
671 - 674
Database
ISI
SICI code
0363-9045(2000)26:6<671:COTPPO>2.0.ZU;2-Y
Abstract
The purpose of this study was to clarify the physicochemical properties of the micelles of platelet-activating factor (PAF; C-18:0) The critical micel le concentration (CMC) of PAF (C-18:0) was determined (0.20 mu M) using flu orescence techniques. The fluidity and the micropolarity of the PAF (C-18:0 ) micelle were similar to those of the micelle of stearoyl lysophosphatidyl choline.