A high-density single-nucleotide polymorphism map of Xq25-q28

A high-density single-nucleotide polymorphism (SNP) map was developed for X q25-q28 using a targeted approach to SNP discovery. This high-density map i ncludes 217 new SNP markers, and 117 are informative in the CEPH parent pop ulation with >20% minor allele frequency. The average distance between SNP markers is 100 kb in the targeted regions. This is the densest genetic map of Xq25-q28 to date. The SNP markers are presented in order by their distan ce in megabases along the X chromosome, and the markers from the current ge netic map are placed using the same scale to produce an integrated map of t he region. (C) 2000 Academic Press.