The objective of this study is to review the published literature on psycho
logical outcome of hysterectomy and oophorectomy for non-malignant indicati
ons. The relevant publications over the past 30 years until the end of 1997
were identified by a MEDLINE computer search. This was followed by hand se
arches of the relevant references in the literature identified by the elect
ronic search. The published studies on the psychological outcome of hystere
ctomy have been selected to identify the incidence, possible causes and ris
k factors of psychological morbidity, and the measures that can be adopted
to improve the outcome.
The study showed that the majority of retrospective studies reported an adv
erse psychological outcome after hysterectomy. However, all prospective stu
dies showed that the incidence of depressed mood is higher even before hyst
erectomy, owing to pre-existing psychiatric illness and personality and psy
chosocial problems, as a result of the emotional response to gynecological
symptoms or as a manifestation of associated ovarian failure. Hence, the th
erapeutic effects of hysterectomy include improvement of mood in some but n
ot all patients, unless proper case selection, psychiatric evaluation and p
reoperative counselling are arranged. An early detection of ovarian failure
after hysterectomy, the initiation of hormone replacement therapy (HRT) im
mediately after surgery in perimenopausal women and in those undergoing oop
horectomy, as well as regular follow-ups to ensure long-term compliance wit
h HRT, would also improve the psychological outcome.
In conclusion hysterectomy itself is not the cause of any adverse psycholog
ical outcome. Psychological symptoms actually improve in the majority of wo
men, with the relief of distressing gynecological symptoms and the correcti
on of ovarian hormone deficiency, but hysterectomy may not be of any benefi
t in women with prior psychiatric illness and those with personality and ps
ychosocial problems.