Objective.-To test the hypothesis that anxiety and depression are associate
d with headache frequency, severity, and disability.
Background.-There is significant comorbidity between chronic headache and p
sychological distress. Headache associated with anxiety or depression tends
to be more severe and often requires supplementary psychological treatment
in addition to headache therapy. Therefore, the identification of patients
with headache who are at risk of psychological distress is important.
Methods.-One hundred twenty-seven consecutive patients with headache attend
ing a university headache clinic were evaluated. Questionnaires about heada
che symptoms and psychological distress were completed. Comparisons were ma
de between psychological distress and headache frequency, severity, and dis
ability.
Results.-Depression and anxiety were significantly greater in the subjects
of this study who had frequent headache (>4 days per week) and frequent hea
dache-associated disability (activities reduced or prohibited because of he
adache >3 days per week). Subjects who reported their headache severity as
typically severe were no more likely to report depression or anxiety than t
hose with mild or moderate headache severity. Quality-of-life measures of p
hysical and social functioning, emotional distress, and general health and
vitality were reduced in subjects with frequent episodes of headache-associ
ated disability. All areas, with the exception of general health perception
, were reduced in subjects with frequent headache. Severe headache was asso
ciated with reductions in role and social functioning.
Conclusions.-Frequent headache and frequent disability are associated with
depression, anxiety, and impaired quality of life. Reports of typical heada
che severity are less likely to correlate with psychological distress. Ther
efore, patients with headache who report frequent headache or frequent peri
ods of headache-related disability should be further evaluated for the pres
ence of psychological disturbance.