Synthesis of 4-[4 '-(N-N-dimethylsulfamoyl)piperazin-1-yl]-pyridine derivatives as sorbitol dehydrogenase potential inhibitors

Authors
Varlet, D Fourmaintraux, E Depreux, P Lesieur, D
Citation
D. Varlet et al., Synthesis of 4-[4 '-(N-N-dimethylsulfamoyl)piperazin-1-yl]-pyridine derivatives as sorbitol dehydrogenase potential inhibitors, HETEROCYCLE, 53(4), 2000, pp. 797-804
Citations number
10
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
53
Issue
4
Year of publication
2000
Pages
797 - 804
Database
ISI
SICI code
0385-5414(20000401)53:4<797:SO4'D>2.0.ZU;2-B
Abstract
A synthesis of various pyridines disubstituted in position 4 by a [4'-(N,N- dimethylsulfamoyl)piperazin-1-yl] group and in position 2 by different func tionalities such as hydrogen, hydroxymethyl, formyl, carboxamido or cyano, is described.