Twenty patients with palmo-plantar pustulosis (10 males and 10 females
) with a mean age of 41+/-6.4 years were compared to 20 controls (10 m
ales and 10 females, mean age 42+/-7.2 years, for possible risk factor
s for palmo-plantar pustulosis, No statistically significant differenc
e was found when the two groups were compared as regards history of at
opy diabetes mellitus and thyroid disease. A statistically significant
difference was found with regard to cigarette smoking (P<0.001) and p
resence of joint symptoms (P<0.01). This pattern, with minor variation
s, is similar to the findings in Western countries. There is a need fo
r increased awareness of this association in developing countries, A l
arger population based study will be highly desirable.