Salmonella enterica serovars typhimurium and Dublin can lyse macrophages by a mechanism distinct from apoptosis

Authors
Watson, PR Gautier, AV Paulin, SM Bland, AP Jones, PW Wallis, TS
Citation
Pr. Watson et al., Salmonella enterica serovars typhimurium and Dublin can lyse macrophages by a mechanism distinct from apoptosis, INFEC IMMUN, 68(6), 2000, pp. 3744-3747
Citations number
33
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
68
Issue
6
Year of publication
2000
Pages
3744 - 3747
Database
ISI
SICI code
0019-9567(200006)68:6<3744:SESTAD>2.0.ZU;2-7
Abstract
Salmonella enterica serovars Typhimurium and Dublin lysed primary bovine al veolar macrophages and immortalized J774.2 macrophage-like cells in the abs ence of either the morphological changes or DNA fragmentation characteristi c of apoptosis. Macrophage lysis mas dependent on a subset of caspases and an intact sipB gene.