Prognostic significance of electrocardiographic change during anginal attack in patients with unstable angina

Objective and Methods We examined the prognostic significance of electrocar diographic change during anginal attack, C-reactive protein and fibrinogen in 169 patients with unstable angina. Results During the 90-day follow-up period, 26 patients (15%) exhibited new cardiac events (death, myocardial infarction or urgent revascularization). Using multivariate analysis, ST depression (relative risk 7.507 [95% confi dence intervals 1,842-30.592], p<0.01) during anginal attack was found to b e an independent risk factor to predict cardiac events as well as diabetes mellitus, an increased total cholesterol level and the use of a thrombolyti c agent. C-reactive protein and fibrinogen did not have prognostic signific ance. Conclusion ST depression during anginal attack is an independent risk predi ctor for new cardiac events in patients with unstable angina.