Dynamic laser speckle pattern in monitoring of local deformation of tabletsurface after compression

Citation
R. Silvennoinen et al., Dynamic laser speckle pattern in monitoring of local deformation of tabletsurface after compression, INT J PHARM, 199(2), 2000, pp. 205-208
Citations number
4
Categorie Soggetti
Pharmacology & Toxicology
Journal title
INTERNATIONAL JOURNAL OF PHARMACEUTICS
ISSN journal
03785173 → ACNP
Volume
199
Issue
2
Year of publication
2000
Pages
205 - 208
Database
ISI
SICI code
0378-5173(20000420)199:2<205:DLSPIM>2.0.ZU;2-J
Abstract
A method and a sensor device were developed to detect dynamic laser speckle pattern for monitoring of deformation of pharmaceutical tablets after comp ression. Temporal variations in optical signal revealed local surface defor mation of the ibuprofen and the starch acetate tablets as well as anisotrop y of tablet surfaces at the inspection location. (C) 2000 Elsevier Science B.V. All rights reserved.