Localized solitary plasmacytoma of the bone (SPB) is a rare disease and is
characterized by only one or two isolated bone lesions with no evidence of
disease dissemination. A previously healthy 44-year-old male was admitted f
or evaluation of an abnormal radiographic shadow in the left middle lung fi
eld with symptoms of left back pain. Radiological evaluation revealed a per
ipheral opacity in the left chest wall, which was highly suspected to be a
chest wall tumor. CT-guided transcutaneous needle biopsy of the tumor was p
erformed and the specimens showed a monomorphous population of mature plasm
a cells. The bone marrow biopsy findings revealed no evidence of myeloma an
d bone scanning revealed only abnormal accumulation in the left seventh rib
. He had mild M-proteins in a urine sample and Bence-Jones protein was dete
cted. Immunoelectrophoresis revealed mild biclonal gammopathy of Bence-Jone
s protein of both the kappa and lambda light-chain types. Under a diagnosis
of solitary bone plasmacytoma, preoperative radiation therapy with doses o
f 40 Gy for the tumor was performed. He underwent complete en bloc resectio
n of the chest wall, including one-third of the left sixth and seventh ribs
, the intercostal muscle and the parietal pleura. The protein abnormalities
in the urine sample disappeared following surgical resection. Adjuvant che
motherapy using melphalan and prednisolone was performed. He is doing well
without evidence of tumor recurrence 2 years following his initial diagnosi
s.