Human tissue analysis by small-angle X-ray scattering

Molecular structure of pathologically changed biological tissue differs gre atly from the normal one. It gives the opportunity to diagnose different di seases by using methods of structural tissue analysis. The present paper is based on Ultra-Low Angle X-ray (ULAX) coherent scattering data from 1000 p aired samples of mammary gland tissue dissected during the surgical treatme nt from 500 patients with different types of breast tumours (malignant or b enign) and tumour-like formations (fibrocystic change). The medical data (h istological and histostereometrical analysis) and the digital scattering in formation have been compared by regression analysis to produce the scatteri ng pattern recognition code that demonstrates the high sensitivity of the U LAX method.