Regioselective synthesis of spiro[naphthalene-2(1H),3 '-[3H]pyrazol]-1-ones utilizing 1,3-dipolar cycloaddition of nitrilimines

Authors
Mishriky, N Girgis, AS Ibrahim, YA
Citation
N. Mishriky et al., Regioselective synthesis of spiro[naphthalene-2(1H),3 '-[3H]pyrazol]-1-ones utilizing 1,3-dipolar cycloaddition of nitrilimines, J CHEM R-S, (1), 2000, pp. 2-3
Citations number
13
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF CHEMICAL RESEARCH-S
ISSN journal
03082342 → ACNP
Issue
1
Year of publication
2000
Pages
2 - 3
Database
ISI
SICI code
0308-2342(200001):1<2:RSOS'>2.0.ZU;2-Q
Abstract
1,3-Dipolar cycloaddition reaction of nitrilimines to a variety of 2-arylme thylidene-3,4-dihydro-1-naphthalenones 1a-h afforded the corresponding spir o[naphthalene-2(1 H),3'-[3H]pyrazol]-1-ones 3 and not the isomeric spiro[na phthalene-2(1H),4'-[4H]pyrazol]-1-ones 4, in high regioselectivity. The str ucture of the isolated products was established through different spectrosc opic techniques and confirmed via HMBC.