An efficient O-dealkylation procedure for the synthesis of (3aS,cis)-1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-yl-3,4-dihydro-2(1H)-isoquinolinecarboxylate
Zl. Gao et al., An efficient O-dealkylation procedure for the synthesis of (3aS,cis)-1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-yl-3,4-dihydro-2(1H)-isoquinolinecarboxylate, J HETERO CH, 37(2), 2000, pp. 331-333
The title compound is synthesized in high yields and purity fr om (-)-esere
thole (2a) via a lithium bromide catalyzed hydrobromic acid O-dealkylation
procedure as the key step.