An efficient O-dealkylation procedure for the synthesis of (3aS,cis)-1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-yl-3,4-dihydro-2(1H)-isoquinolinecarboxylate

Authors
Gao, ZL Lee, TBK Rauckman, BS
Citation
Zl. Gao et al., An efficient O-dealkylation procedure for the synthesis of (3aS,cis)-1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-yl-3,4-dihydro-2(1H)-isoquinolinecarboxylate, J HETERO CH, 37(2), 2000, pp. 331-333
Citations number
27
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022152X → ACNP
Volume
37
Issue
2
Year of publication
2000
Pages
331 - 333
Database
ISI
SICI code
0022-152X(200003/04)37:2<331:AEOPFT>2.0.ZU;2-8
Abstract
The title compound is synthesized in high yields and purity fr om (-)-esere thole (2a) via a lithium bromide catalyzed hydrobromic acid O-dealkylation procedure as the key step.