Synthesis of novel 5H,11H-pyrido[2 ',3 ': 2,3]thiopyrano[4,3-b]-indoles byFischer-indole cyclization

Authors
Da Settimo, A Marini, AM Primofiore, G Da Settimo, F Salerno, S La Motta, C Pardi, G Ferrarini, PL Mori, C
Citation
A. Da Settimo et al., Synthesis of novel 5H,11H-pyrido[2 ',3 ': 2,3]thiopyrano[4,3-b]-indoles byFischer-indole cyclization, J HETERO CH, 37(2), 2000, pp. 379-382
Citations number
13
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022152X → ACNP
Volume
37
Issue
2
Year of publication
2000
Pages
379 - 382
Database
ISI
SICI code
0022-152X(200003/04)37:2<379:SON5''>2.0.ZU;2-T
Abstract
The synthesis of the title compounds 5H,11H-pyrido[2',3':2,3]thiopyrano[4,3 -b]indoles was accomplished by the Fischer indole cyclization of some 2,3-d ihydrothiopyrano[2,3-b]pyridin-4(4H)-one phenylhydrazones and 7-methyl-2,3- dihydrothiopyrano[2,3-b]pyridin-4(4H)-one phenylhydrazones. The synthesis o f the new 2,3-dihydrothiopyrano[2,3-b]pyridin-4(4H)-one, which was used as one of the starting compounds, is also described.