New taxanes with an opened oxetane ring from the roots of Taxus mairei

Citation
Yc. Shen et al., New taxanes with an opened oxetane ring from the roots of Taxus mairei, J NAT PROD, 63(5), 2000, pp. 720-722
Citations number
13
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
5
Year of publication
2000
Pages
720 - 722
Database
ISI
SICI code
0163-3864(200005)63:5<720:NTWAOO>2.0.ZU;2-H
Abstract
Two novel taxoids, taxmairols N (1) and O (2), have been isolated from extr acts of the roots of Taxus mairei. The structures of 1 and 2 were identifie d as 7 beta,9 alpha,10 beta,13 alpha-tetraacetoxy-2 alpha,4 alpha,5 alpha,- 20-tetrahy- droxytax-11-ene and 7 beta,9 alpha,10 beta,13 alpha-tetraacetox y-1 beta,2 alpha,4 alpha,5 alpha,20-pentahydroxytax-11-ene on the basis of 1D and 2D NMR techniques including COSY, HMQC, HMBC, and NOSEY experiments.