Integration of spatial and time methods in neuroimaging

The combination of functional neuroimaging using PET or fMRI with electroph ysiological methods having high temporal resolution permits a detailed spat io-temporal analysis of cerebral information processing. Several requiremen ts have to be met for the successful integration of diverse imaging methods : 1) paradigms have to be developed that can be used with both classes of t echniques, 2) a common coordinate system should be employed. We illustrate the possibilities of combined neuroimaging by several recent examples. More over, prospective clinical applications are discussed.