The most important single factor affecting the efficiency of protein utiliz
ation is the profile of digestible essential amino acids entering the, smal
l intestine. Assuming a constant ideal amino acid profile of absorbed prote
in the requirements of all amino acids can be calculated when the requireme
nt of one individual amino acid has been determined. In non-ruminants, the
supply will be greatly influenced by the diet, but less so in ruminants due
to the rumen microbial degradation of feed protein and synthesis of microb
ial protein with high biological value. However, the high-producing dairy c
ow requires a significant amount of numen escape protein. Thus, the profile
of the undegraded feed protein could influence the profile of the amino ac
ids entering the small intestine to a point at which individual amino acids
become limiting. For non-ruminants, lysine is usually the first limiting a
mino acid in feedstuffs. This has led to the general practice of expressing
the requirements for all other essential amino acids relative to lysine. A
lternatively, the amino acid requirements can be expressed relative to N. T
hen, dietary N required for synthesis of other N-compounds is also included
. Moreover, the requirements of all amino acids can be calculated when the
N requirement has been determined. However, this method cannot be used for
ruminants, because the N requirement of rumen microbes may be higher than t
he requirement of the animal. In the future, computerised animal models bas
ed on scientifically correct feed evaluation systems offer the opportunity
for securing optimal feeding of farm animals in relation to their ideal ami
no acid profile for all different purposes of production. (C) 2000 Publishe
d by Elsevier Science B.V. All rights reserved.