Synaptic plasticity and dynamic modulation of the portsynaptic membrane

Authors
Luscher, C Nicoll, RA Malenka, RC Muller, D
Citation
C. Luscher et al., Synaptic plasticity and dynamic modulation of the portsynaptic membrane, NAT NEUROSC, 3(6), 2000, pp. 545-550
Citations number
75
Categorie Soggetti
Neurosciences & Behavoir
Journal title
NATURE NEUROSCIENCE
ISSN journal
10976256 → ACNP
Volume
3
Issue
6
Year of publication
2000
Pages
545 - 550
Database
ISI
SICI code
1097-6256(200006)3:6<545:SPADMO>2.0.ZU;2-2
Abstract
The biochemical composition of the postsynaptic membrane and the structure of dendritic spines may be rapidly modulated by synaptic activity. Here we review these findings, discuss their implications for long-term potentiatio n (LTP) and long-term depression (LTD) and propose a model of sequentially occurring expression mechanisms.