Within neurodegenerative disease gender differences ore minor. The incidenc
e and prevalence of the major dementing disorders, for example, are about e
qual. Nevertheless, in particular genetic and hormonal influences must be t
aken into account. It is well known that men excel in mental rotation tasks
, while women ore superior in memorizing objects. Some studies emphasize a
reduced functional asymmetry of the hemispheres in females. As regards Alzh
eimer's disease women are mildly more impaired cognitively, hut their longe
r survival increases the prevalence rate in The oldest age group. Whether t
heir mental impairments may be lessened using estrogen substitution is stil
l a matter of debate. Women are more often care-givers for physically and m
entally handicapped peers than men. A few genetic and degenerative disease
ore met mostly or exclusively in females, such as Goltz-Gorlin's syndrome,
Rett's syndrome, Bloch-Sulzberger's syndrome, Meige's syndrome, Triplo-X an
d Turner's syndrome.