I. Malcic et al., Radioangioscintigraphy and Doppler echocardiography in the quantification of left-to-right shunt, PEDIAT CARD, 21(3), 2000, pp. 240-243
The magnitude of left-to-right shunt in 55 children with isolated congenita
l heart disease [atrial septal defect (ASD) or ventricular septal defect (V
SD) (muscular and perimembranous)] was estimated by two methods: radionucli
de quantification and Doppler echocardiography [flow (L/min) = mean velocit
y x area x ejection time x heart rate]. We found little difference between
the magnitude of left-to-right shunt obtained with Doppler echocardiography
and that with radioangioscintigraphy for a whole group of patients (N = 55
, -11.42% to 12.04%) and for subgroups of ASD (n = 24, -12.49% to 12.19%) a
nd VSD (n = 31, -10.69% to 12.23%). These results indicate that Doppler ech
ocardiography, in comparision with radioangioscintigraphy, is sufficiently
accurate for clinical estimation of the Q(p)/Q(s) ratio in isolated congeni
tal heart disease with left-to-right shunt.