Citation
G. Oster et al., How F-o-ATPase generates rotary torque, PHI T ROY B, 355(1396), 2000, pp. 523-528
Citations number
31
Categorie Soggetti
Multidisciplinary,"Experimental Biology
Journal title
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
ISSN journal
09628436
→ ACNP
Volume
355
Issue
1396
Year of publication
2000
Pages
523 - 528
Database
ISI
SICI code
0962-8436(20000429)355:1396<523:HFGRT>2.0.ZU;2-O
Abstract
The F-ATPases synthesize ATP using a transmembrane ionmotive force (IMF) es
tablished by the electron transport chain. This transduction involves first
converting the IMF to a rotary torque in the transmembrane F-0 portion. Th
is torque is communicated from F-0 to the F-1 portion where the energy is u
sed to release the newly synthesized ATP from the catalytic sites according
to Boyer's binding change mechanism. Here we explain the principle by whic
h an IMF generates this rotary torque in the F-0 ion engine.