We focus on the deceptively simple question: how can we use the emitted pho
tons to extract meaningful information on the transition region and corona?
Using examples, we conclude that the only safe way to proceed is through f
orward models. In this way, inherent non-uniqueness is handled by adding in
formation through explicit physical assumptions and restrictions made in th
e modeling procedure. The alternative, 'inverse' approaches, including (as
a restricted subset) many standard' 'spectral diagnostic techniques', rely
on more subjective choices that have, as yet, no clear theoretical support.
Emphasis is on the solar transition region, but necessarily discussing the
corona, and with implications for more general problems concerning the use
of photons to diagnose plasma conditions.